These beneficial effects might open up new avenues in the prevention of diabetes. Subjects with a higher FPG level and a milder inflammatory state at baseline benefited most from the dietary supplement.įour-month treatment with a dietary supplement containing cinnamon, chromium and carnosine decreased FPG and increased fat-free mass in overweight or obese pre-diabetic subjects. Although there were no significant differences in changes in body weight and energy or macronutrient intakes between the two groups, fat-free mass (%) increased with the dietary supplement compared to placebo (p = 0.02). Insulin sensitivity markers, plasma insulin, plasma lipids and inflammatory markers did not differ between the treatment groups. Cinnamon might increase insulin sensitivity and improve glucose uptake into cells.
Patients were followed up until 6 months post-randomization.įour-month treatment with the dietary supplement decreased FPG compared to placebo (-0.24☐.50 vs +0.12☐.59 mmol/L, respectively, p = 0.02), without detectable significant changes in HbA1c. Cinnamon and chromium benefits Helps promote sugar metabolism when combined with a healthy diet and exercise program. If cinnamon does decrease fasting glucose levels in patients with type 2 diabetes, it likely does so by decreasing insulin resistance. The combination of a low GL diet, with chromium and cinnamon.
In a randomized, double-blind, placebo-controlled study, 62 subjects with a FPG level ranging from 5.55 to 7 mmol/L and a body mass index ≥25 kg/m2, unwilling to change their dietary and physical activity habits, were allocated to receive a 4-month treatment with either 1.2 g/day of the dietary supplement or placebo. One to three capsules a day are recommended, in conjunction with a low Glycemic Load (GL) diet. Other parameters of plasma glucose homeostasis, lipid profile, adiposity and inflammatory markers were also assessed. Our aim was to evaluate the effects of 4-month treatment with a dietary supplement containing cinnamon, chromium and carnosine in moderately obese or overweight pre-diabetic subjects, the primary outcome being change in fasting plasma glucose (FPG) level. For both supplemental Cr and cinnamon not all studies have reported beneficial effects and the responses are related to the duration of the study, form of Cr or cinnamon used and the extent of obesity and glucose intolerance of the subjects.Preventing or slowing the progression of prediabetes to diabetes is a major therapeutic issue. Studies utilizing an aqueous extract of cinnamon, high in type A polyphenols, have also demonstrated improvements in fasting glucose, glucose tolerance and insulin sensitivity in women with insulin resistance associated with the polycystic ovary syndrome. Subjects with the metabolic syndrome who consume an aqueous extract of cinnamon have been shown to have improved fasting blood glucose, systolic blood pressure, percentage body fat and increased lean body mass compared with the placebo group. Cinnamon reduces mean fasting serum glucose (18-29%), TAG (23-30%), total cholesterol (12-26%) and LDL-cholesterol (7-27%) in subjects with type 2 diabetes after 40 d of daily consumption of 1-6 g cinnamon. It has also been shown that cinnamon polyphenols improve insulin sensitivity in in vitro, animal and human studies.
In a double-blind placebo-controlled study it has been demonstrated that glucose, insulin, cholesterol and HbA1c are all improved in patients with type 2 diabetes following Cr supplementation. Several studies done on humans have shown that cinnamon is able to reduce glucose blood levels and increase insulin sensitivity, as well as lower LDL. The signs of Cr deficiency are similar to those for the metabolic syndrome and supplemental Cr has been shown to improve all these signs in human subjects. Solomon and his team of researchers concluded that the ingestion of cinnamon reduced total plasma-glucose and improved insulin-sensitivity in the particpants. The active ingredient in cinnamon, MCHP mimics the action of the hormone insulin, which removes excess sugar from the bloodstream.
These compounds also have similar effects on insulin signalling and glucose control. Cinnamon and chromium a winning combination Cinnamon, together with chromium, helps normalise blood sugar and reduce insulin resistance. Naturally-occurring compounds that have been shown to improve insulin sensitivity include Cr and polyphenols found in cinnamon (Cinnamomon cassia). NutriFlair Ceylon Cinnamon, Berberine HCL, Chromium, Black Pepper Extract (Made with True Ceylon Cinnamon) - 1200mg per Serving, 120 Capsules - Glucose. Additionally, recent work suggests that cinnamon (Cinnamomum spp., Lauraceae) bark, along with chromium and magnesium, may increase insulin sensitivity.
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